British Journal of Dermatology 19997:136: 772-775. Oral melanotic macules do not cause an increase in the number of melanocytes and are not associated with a predisposition to melanoma. Intense pulsed light therapy which is a form of laser therapy. If a skin biopsy is done because the lesion is changing or looks irregular, a labial melanotic macule shows the following features on dermatopathology: Nuclear atypia is absent and the melanocyte count is normal. Oral melanotic macule (MM) is a small, well-circumscribed, brown-to-black macule, and about of 665 cases has been reported in the English literature (2). [1] Oral pigmented lesions result from cellular hyperplasia that can range from benign nevi to fatal oral melanoma. Author: Dr Mark Duffill, Dermatologist, Hamilton, New Zealand, 2008. Multiple lentiginosis (various syndromes including. Excision can also be performed but will leave a scar. But before we proceed, we have to acknowledge that this condition is not related to systemic diseases or sunlight. The presence of numerous melanotic macules on the body may be associated with a variety of syndromes including Carney complex, Peutz-Jeghers syndrome, and LEOPARD syndrome. Some of those causes can include: Being born with one or having it appear in early childhood, which is common for people who have dark skin. Labial melanotic macule (low power); mild acanthosis without elongation of rete ridges. These conditions can be differentiated from labial melanotic macule by a combination of clinical and histological features. Genetic disorders 2. A labial melanotic macule is thought to be provoked by sun exposure, and it is more common in fair-skinned people. 1,2 The oral melanotic macule presents in patients older than 40 years as a flat, blue, brown, or black, mostly solitary lesion less than 10 mm in diameter. Melanin is a normal skin pigment that gives the skin its darker color. Oral melanotic macule and primary oral malignant melanoma: epidemiology, location involved, and clinical implications. It has also been found on the genital areas. H Arch Dermatol. It may also arise on the gingival, buccal, or palatal mucosa. It is suggested that the term oral melanotic macule be used for these lesions, unless a specific cause can be confirmed by clinical data. A variation of the melanotic macule is the ephelis, or freckle, which generally appears as a small (2- to 3-mm) brown spot on the lip. Lesions can also be found in the mouth (oral melanotic macule), on the vulva (vulval labial melanotic macule; vulval melanosis) or on the penis (penile melanotic macule). It can even be found on the inside of your mouth, gums, called gingiva, the roof your mouth on the soft or hard palate, or inner cheek called buccal mucosa. Luckily, melanotic macules are harmless. Although it can appear at any age in either sex, race, or gender, it is most commonly found in people who are dark skinned and in their middle ages and are female. DermNet provides Google Translate, a free machine translation service. Causes List for Hypermelanotic macule. Conditions that are likely to cause macules are: vitiligo; moles; freckles Clinically presentation of melanotic macules are typically a brown, black, blue or grey area that is well circumscribed, lesions are usually less than 10 mm in diameter but can be larger in some cases. Diagnosis confirmation. Note that this may not provide an exact translation in all languages, breadcrumbs [Sponsored content]. Contact us to sponsor a DermNet newsletter. Melanotic Macule Causes There is a variety of causes for a person to have a melanotic macule. It is also sometimes called a labial lentigo and when multiple lesions are present, mucosal melanosis. Sponsored content: melanomas are notoriously difficult to discover and diagnose. Multiple lesions may be a sign of a widespread skin condition, such as: A labial melanotic macule has a characteristic pattern when examined with the magnifying glass or by dermoscopy. 7,8 Congenital lingual melanotic macules represent a clinically distinct and benign cause of hyperpigmentation of the oral mucosa. A melanotic macule is a small dark spot that is usually benign, but may be a cause for concern if it changes in color, shape, or texture. Home Their etiology is not clear and it may represent a physiologic or reactive process. According to RDH Magazine, this common oral condition is present in 3 percent of the general population and is caused by a … In some people, if they opt to have it removed the tissue may heal well and leave little or no depression or scar. There is a variety of causes for a person to have a melanotic macule. A labial melanotic macule may be confused with another pigmented skin lesion. With your help, we can update and expand the website. Oral melanotic macules may have more of a predilection toward malignant melanoma than LMM. The oral melanotic macule (MM) is a small, well-circumscribed brown-to-black macule that occurs on the lips and mucous membranes. A melanotic macule is a benign pigmented lesion of oral cavity characterised by increase in melanin pigmentation. Similar freckles may also occur in areas that are not exposed to the sun: Labial melanotic macules do not cause any symptoms but their appearance can be a concern to the patient. Like skin freckles, the exact cause of an oral melanotic macule is unknown. Excision but using this form of removal will leave you a scar. Currently, there is no specific cause for this vulvar benign but there are some rarely linked factors. Histologically, this is evidenced by abundant melanin pigmentation within the basal epithelial cell layer with melanin incontinence in … It is the name for a freckle arising on the lip. 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